info@epichembio.eu + 34 986 812 316

Department of Molecular Cardiology and Angiology

Yahya.Sohrabi@ukmuenster.de
http://klinikum.uni-muenster.de
Address

Germany
Keywords

Albert-Schweitzer-Campus 1, Building D3 Room 0.005, D-48149 Münster

Models

human peripheral monocytes/macrophages, murine monocytes/macrophages, neutrophils, smooth muscle cells

Techniques

Flow cytometry and cell sorting, Histolgy, Confocal and florescent microscopy, Cell culture, RNA and protein analysis, ChIP assay, cytokine and chemokine secretion assays, trasfection

Collaborations outside COST

Our group has established collaboration with different labs in European countries and other part of the word

Short description of ongoing research projects

My current research projects are focused on epigenetic regulation of innate immune memory. I am also interested in studying epigenetic regulation of phenotype switching in monocytes/macrophages and smooth muscle cells. We are also studying cross talk between different innate immune cells like monocytes/macrophages and neutrophils and their role in development of atherosclerosis.

Publications
  1. Sohrab, Y., Havelkova, H., Kobets, T., Sima M. Volkova, V. Grekov, I., Jarosikova, T., chicken, I., Vojtiskova, J., Svobodova, M., Demant, P., Lipoldova, M. Mapping the Susceptibility Genes for and Response to Leishmania tropica in Mouse (2013) PLoS Neglected Tropical Diseases, 7 (7), art. no. e2282.
  2. Khamesipour, A., Nateghi Rostami, M., Tasbihi, M., Miramin Mohammadi, A., Shahrestani, T., Sarrafnejad, A., Sohrabi, Y., Eskandari, SE, Keshavarz Valian, H. Phenotyping of circulating CD8 + T cell subsets in human cutaneous leishmaniasis (2012) microbes and infectious, 14 (9), pp. 702-711.
  3. Kobets, T., Havelkova, H., Grekov, I., Volkova, V., Vojtísková, J., Slapnicková, M., chicken, I., Sohrab, Y., Svobodová, M., Demant, P., Lipoldová, M.Genetics of host response to Leishmania tropica in mice - control of different skin pathology, chemokine Reaction, and invasion into spleen and liver (2012) PLoS Neglected Tropical Diseases, 6 (6), art. no. e1667.
  4. Lipoldová, M., Havelková, H., Badalová, J., Vojtísková, J., Quan, L., Krulová, M., Sohrabi, Y., Stassen, A.P., Demant, P. Loci controlling lymphocyte production of interferon γ after alloantigen stimulation in vitro and their co-localization with genes controlling lymphocyte infiltration of tumors and tumor susceptibility (2010) Cancer Immunology, Immunotherapy, 59 (2), pp. 203-213.
Other activities of potential interest to others


Cost UE