Division of Human Genome Research Centre, Vilnius University

sonata.jarmalaite@gf.vu.lt
www.vu.lt/en

Address

Ciurlionio 21, LT-03101 Vilnius
Lithuania

Keywords

DNA methylation, miRNA, gene expression, cancer, stem cells

Models

clinical material, cell lines

Techniques

Next generation sequencing, microarrays, TaqMan arrays, pyrosequencing, real-time PCR, MSP

Collaborations outside COST

Finnish Institute of Occupational Health, Finland; Friedrich-Alexander-Universität Erlangen-Nürnberg, Germany; Centre for Addiction and Mental Health, Canada;

Short description of ongoing research projects

Epigenetic and genetic profile of human cancer (prostate, breast, head and neck, lung); Epigenetic regulation of mesenchymal stem cells differentiation; Cancer stem cells

Publications

Juzėnas S, Saltenienė V, Kupcinskas J, Link A, Kiudelis G, Jonaitis L, Jarmalaite S, Kupcinskas L, Malfertheiner P, Skieceviciene J. Analysis of deregulated microRNAs and their target genes in gastric cancer. PLoS One. 2015 Jul 14;10(7):e0132327.
Daniunaite K, Jarmalaite S, Kalinauskaite N, Petroska D, Laurinavicius A, Lazutka JR, Jankevicius F. Prognostic value of RASSF1 promoter methylation in prostate cancer. J Urol. 2014 Dec;192(6):1849-55.
Scesnaite A, Jarmalaite S, Mueller M, Agaimy A, Zenk J, Hartmann A, Peters B, Schwarz S, Schneider-Stock R. Prognostic value of MGMT loss in salivary gland carcinomas. Head and Neck. 2014 Sep;36(9):1258-67.
Cortese R, Kwan A, Lalonde E, Bryzgunova O, Bondar A, Wu Y, Gordevicius J, Park M, Oh G, Kaminsky Z, Tverkuviene J, Laurinavicius A, Jankevicius F, Sendorek DH, Haider S, Wang SC, Jarmalaite S, Laktionov P, Boutros PC, Petronis A. Epigenetic markers of prostate cancer in plasma circulating DNA. Hum Mol Genet. 2012 Aug 15;21(16):3619-31.
Sabaliauskaite R, Jarmalaite S, Petroska D, Dasevicius D, Laurinavicius A, Jankevicius F, Lazutka JR. Combined Analysis of TMPRSS2-ERG and TERT for Improved Prognosis of Biochemical Recurrence in Prostate Cancer. Genes Chromosomes Cancer. 2012 Aug; 51(8):781-91.