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AParaDDisE

Workshop in Rome: Epigenetic drug discovery for Neglected Parasitic Diseases

November 7, 2016

Two-day workshop will take place in Rome on November 30 – December 1 2016 (Hotel Massimo D’Azeglio, closeby Termini station). It is organized by the EU-funded A-ParaDDisE project consortium. There is no registration fee but participation will be limited to the first 100 candidates registering on the website: http://truta.cebio.org/a-workshop

Epigenetic processes are increasingly being investigated for the development of novel therapies for a variety of pathologies including parasitic diseases.

The readers, writers and erasers of post-translational modifications of histone tails, and especially those involved in acetylation and methylation of lysine residues are the targets of a variety of drugs and drug candidates.

The workshop will address both the strategies for developing “epi-drugs” in general and their application to the Neglected Parasitic Diseases, including target identification and validation, screening methods and hit-to-lead development.

Invited speakers include Stuart Conway (Oxford University), Henk Stunnenberg (Radboud University), Lucia Altucci (Naples University) and Fabrizio Micheli (Aptuit, Verona). See the website for the program and full list of speakers.



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